On April 29, 2024, The US Food and Drug Administration (FDA) has accepted a Supplemental New Drug Application for tapinarof cream, 1%, for the topical treatment of atopic dermatitis in adults and children aged ≥ 2 years, according to an announcement by the manufacturer, Dermavant Sciences. Tapinarof cream, 1% (VTAMA) is a steroid-free aryl hydrocarbon […]
TDM-180935 is a small-molecule drug candidate intended to treat atopic dermatitis. Credit: Kaspars Grinvalds / Shutterstock. Chinese biopharmaceutical company Technoderma Medicines has begun dosing patients in its Phase IIa clinical trial of topical TDM-180935 ointment, a potential treatment for atopic dermatitis (AD). The eight-week trial will assess the two different strengths of the topical medication […]
Stress causes a spike in the hormone cortisol, which may lead to eczema flare-ups. Avoiding stress and other triggers may help reduce flares. Atopic dermatitis, known as eczema, is a chronic inflammatory condition that may cause dry, itchy rashes to develop on your skin. These can sometimes be painful and could lead to feelings of […]
For the second time in four years, AbbVie’s Rinvoq (upadacitinib) has shown superior efficacy to Regeneron and Sanofi’s powerhouse Dupixent (dupilumab) in a head-to-head study in patients with atopic dermatitis (AD). In the LEVEL UP trial testing patients age 12 and older with moderate-to-severe AD who had an inadequate response to systemic therapy, 20% of […]